Khat (Catha edulis) Exacerbate Insulin Resistance in A High-Fat Diet/Streptozotocin-Induced Rat Model of Type 2 Diabetes Mellitus
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چکیده
منابع مشابه
Catha Edulis (khat), a Sex Depressant, Euphoriant in History
This article traces the history of the Khat which is an intoxicant and also a sexual depressant. The author establishes that its origion is Abyssinia and it is brought to Arabia where it is commonly used even by Muslims. If Khat is consumed in excess it may impair the health but moderate quantity is beneficial.
متن کاملSevere rhabdomyolysis associated with catha edulis(khat) use
Severe rhabdomyolysis is a rare complication of exposure to the recreational drug khat. Adverse reactions to khat that have been reported in the literature include myocardial infarction and reversible vasoconstriction syndrome. The active ingredient, cathinone, is a naturally occurring beta-ketone amphetamine that may be responsible for this severe catecholaminergic response. Here we report a c...
متن کاملInsulin Resistance, a surrogate marker, in type 2 Diabetes Mellitus
Type 2 diabetes mellitus (T2DM) is an insulin resistant state associated with accelerated atherosclerosis, hypertension, dyslipidemia and abnormal vasomotor responses to insulin. One hundred and thirty nine T2DM patients were included in this study. Out of the total 139 patients, 120 (86.33%) had hyper-insulinemia. According to the NCEP-ATP III criteria, the prevalence of IRS was 103 (74.1%) am...
متن کاملAssessment of khat (Catha edulis Forsk) 1. Substance Identification
F. WHO Review History: The WHO Expert Committee on Drug Dependence (ECDD) and other UN bodies reviewed khat at earlier occasions. The Advisory Committee on the Traffic in Opium and Other Dangerous Drugs of the League of Nations discussed on the subject in 1933, but no action was taken. On request of the Commission on Narcotics Drugs (CND), the Expert Committee on Addiction-Producing Drugs (as t...
متن کاملCatha edulis Forsk. (Khat): Evaluation of its Antidepressant-like Activity
BACKGROUND Catha edulis Forsk. (Khat) is traditionally used for treating various disorders. Nevertheless there are no reports of any scientific assessment of its psychopharmacological properties. OBJECTIVE Therefore, the current study was designed to evaluate the antidepressant-like activity of Khat ethanolic extract using established animal models of depression and stress. MATERIALS AND ME...
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ژورنال
عنوان ژورنال: Metabolism
سال: 2021
ISSN: 0026-0495
DOI: 10.1016/j.metabol.2020.154546